Summary
Studies on the sarcomere length-force relation in Ca++-activated vertebrate muscle myofibrils indicate that the maximum isometric force can be generated even at sarcomere lengths around 1 μm, indicating that the ascending limb of the sarcomere length-force relation is virtually absent.
References
Gordon, A.M., Huxley, A.F., and Julian, F.J., J. Physiol.184 (1966) 170.
Taylor, S.R., and Rüdel, R., Science167 (1970) 882.
Schoenberg, M., and Podolsky, R.J., Science172 (1972) 52.
Moss, R.L., J. Physiol.292 (1979) 177.
Tanaka, H., Tanaka, M., and Sugi, H., J. Biochem. Tokyo86 (1979) 1587.
Fabiato, A., and Fabiato, F., J. Physiol., London249 (1975) 469.
Portzehl, H., Caldwell, P.C., and Rüegg, J.C., Biochim. biophys. Acta79 (1964) 581.
Julian, F.J., and Moss, R.L., J. Physiol.304 (1980) 529.
Lopez, J.R., Wanek, L.A., and Taylor, S.R., Science214 (1981) 79.
Author information
Authors and Affiliations
Additional information
We thank Miss S. Gomi for her technical assistance. This work was supported by the grant (No. 587028) form the Ministry of Education, Science and Culture of Japan.
Rights and permissions
About this article
Cite this article
Sugi, H., Ohta, T. & Tameyasu, T. Development of the maximum isometric force at short sarcomere lengths in calcium-activated muscle myofibrils. Experientia 39, 147–148 (1983). https://doi.org/10.1007/BF01958866
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01958866