European Journal of Pediatrics

, Volume 150, Issue 7, pp 507–508 | Cite as

Can high-dose immunoglobulin therapy be indicated in neonatal rhesus haemolysis?

A successful case of haemolytic disease due to rhesus (c+E) incompatibility
  • S. Kubo
  • T. Ariga
  • H. Tsuneta
  • T. Ishii
Neonatology

Abstract

A male neonate with hyperbilirubinaemia and progressing anaemia due to rhesus (c+E) incompatibility received high dose intravenous gammaglobulin (ivIgG) therapy at 13 days of age. Clinical response to therapy was confirmed by a rapid decrease in serum bilirubin level, and with the prevention of a further decline of the haemoglobin level. No side-effects were noted. High dose ivIgG therapy could be an alternative to (exchange) blood transfusion in case of some haemolytic diseases of newborn.

Key words

High dose intravenous gammaglobulin therapy Haemolytic disease of newborn Rhesus incompatibility 

Abbreviations

ivIgG

high-dose intravenous gammaglobulin

HND

haemolytic disease of newborn

Rh

rhesus

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Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • S. Kubo
    • 1
  • T. Ariga
    • 1
  • H. Tsuneta
    • 1
  • T. Ishii
    • 1
  1. 1.Department of PaediatricsHokkaido Central Hospital for Social Health InsuranceSapporoJapan

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