European Journal of Pediatrics

, Volume 150, Issue 7, pp 470–472 | Cite as

Persistence of parvovirus B19-DNA in blood of a child with severe combined immunodeficiency associated with chronic pure red cell aplasia

  • M. Gahr
  • A. Pekrun
  • H. Eiffert


In a female child with severe combined immunodeficiency, pure red cell aplasia was observed which required regular transfusions of erythrocytes Parvovirus B 19 DNA (but no antibodies) was detected in stored serum samples after the death of the patient. We suggest that the anaemia was a consequence of parvovirus infection which persisted for at least 2 years due to the immunodeficiency.

Key words

Parvovirus B 19 Severe combined immunodeficiency Pure red cell anaemia 



severe combined immunodeficiency


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Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • M. Gahr
    • 1
  • A. Pekrun
    • 1
  • H. Eiffert
    • 2
  1. 1.Universitäts-Kinderklinik GöttingenGöttingenGermany
  2. 2.Hygiene-InstitutUniversität GöttingenGöttingenGermany

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