Persistence of parvovirus B19-DNA in blood of a child with severe combined immunodeficiency associated with chronic pure red cell aplasia
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In a female child with severe combined immunodeficiency, pure red cell aplasia was observed which required regular transfusions of erythrocytes Parvovirus B 19 DNA (but no antibodies) was detected in stored serum samples after the death of the patient. We suggest that the anaemia was a consequence of parvovirus infection which persisted for at least 2 years due to the immunodeficiency.
Key wordsParvovirus B 19 Severe combined immunodeficiency Pure red cell anaemia
severe combined immunodeficiency
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