Abstract
We report three brothers who developed nephrosis between the age of 3–10 years. The parents were nonconsanguineous and of Arab descent. The mother's sister had a son with a similar condition. Patients were steroid responders and frequent relapsers. Renal biopsies in the three brothers showed findings of minimal change nephrosis. This family may suggest the existence of an X-linked recessive nephrosis which provides further evidence for genetic heterogeneity of familial nephrosis.
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Abbreviations
- MCN:
-
minimal change nephrosis
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Awadalla, N.B., Teebi, A.S., Elzouki, A.Y. et al. Frequent relapser minimal change nephrosis: An unrecognized X-linked disorder?. Eur J Pediatr 149, 205–207 (1989). https://doi.org/10.1007/BF01958283
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DOI: https://doi.org/10.1007/BF01958283