Skip to main content
SpringerLink
Log in

No reduction of high density lipoprotein2 during weight reduction in obese children and adolescents

  • Metabolic Diseases
  • Published:
European Journal of Pediatrics Aims and scope Submit manuscript

Abstract

The effects of a 3 week weight reduction regimen on lipids and lipoproteins, in particular high density lipoprotein (HDL)-subfractions in 61 grossly obese children and adolescents (37 females and 26 males) aged 11–15 years were studied. Dietary treatment resulted in a significant weight reduction of initial body weight of 9.6±2.1%, a highly significant decrease in cholesterol, low density lipoprotein cholesterol (LDL-C) and HDL-C (P<0.001), as well as a significant reduction in triglycerides, HDL3 and Apolipoprotein B concentrations (P<0.01). HDL2 concentrations remained almost constant. It is concluded that HDL reduction during a weight reducing regimen in adolescents does not result in a decrease of the antiatherogenic HDL2 subfraction.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Abbreviations

HDL-C:

high density lipopotein cholesterol

LDL-C:

low density lipoprotein cholesterol

TC:

total cholesterol

TG:

triglycerides

References

  1. Berchtold P, Berger M, Jörgens V, Daweke C, Chantelau E, Gries FA, Zimmermann H (1981) Cardiovascular risk factors and HDL-cholesterol levels in obesity. Int J Obes 5:1–10

    Google Scholar 

  2. Gordon T, Castelli WP, Hjortland MC, Kannel WB, Dawber TR (1977) High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study. Am J Med 62:707–714

    PubMed  Google Scholar 

  3. Manual of Laboratory operations. Lipid Research Clinics Program (1974) Vol I. Lipid and lipoprotein analysis. DHEW, Bethesda, pp 75–628

    Google Scholar 

  4. Talameh Y, Wei R, Naito H (1986) Measurement of total HDL, HDL2 and HDL3 by dextran sulfate-MgCl precipitation technique in human serum. Clin Chim Acta 158:33–41

    PubMed  Google Scholar 

  5. Widhalm K, Zwiauer K (1983) Lipids and lipoproteins in obese adolescents during a very low calorie diet (VLCD). Int J Obes 7: 599–600

    PubMed  Google Scholar 

  6. Widhalm K, Zwiauer K (1984) Lipids, lipoproteins and fatty acid composition in obese adolescents undergoing a very low calorie diet. Clin Nutr 3:209–214

    Google Scholar 

  7. Zimmerman J, Kaufmann NA, Fainaru M, Eisenberg S, Oschry Y, Friedlander Y, Stein Y (1984) Effect of weight loss in moderate obesity on plasma lipoprotein and apolipoprotein levels and on high density lipoprotein composition. Atherosclerosis 4:115–123

    Google Scholar 

  8. Zwiauer K, Widhalm K, Strobl W (1986) Apolipoproteine und Lipoproteine während rascher Gewichtsreduktion und nach einem 6 Monate Follow up. Akt Ernährung 11:57

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Paediatrics, University of Vienna, Währinger Gürtel 18-20, A-1090, Vienna, Austria

    K. Zwiauer, B. Kerbl & K. Widhalm

Authors
  1. K. Zwiauer
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. B. Kerbl
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. K. Widhalm
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Zwiauer, K., Kerbl, B. & Widhalm, K. No reduction of high density lipoprotein2 during weight reduction in obese children and adolescents. Eur J Pediatr 149, 192–193 (1989). https://doi.org/10.1007/BF01958279

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01958279

Key words

Search

Navigation