, Volume 47, Issue 3, pp 292–296 | Cite as

Metabolism of pyridine and 3-hydroxypyridine under aerobic, denitrifying and sulfate-reducing conditions

  • J. -P. Kaiser
  • J. -M. Bollag
Research Articles


The transformation of pyridine and several hydroxypyridines was investigated under different physiological conditions. Pyridine and 2-, 3- and 4-hydroxypyridine were metabolized aerobically within 9 days in a mineral salt medium inoculated with 10% sewage sludge. Under anaerobic conditions in the presence of nitrate or sulfate, pyridine and 3-hydroxypyridine were metabolized after a lag period of 2 months, while no transformation of 2- or 4-hydroxypyridine was detected. Experiments with14C-labeled-pyridine showed that under denitrifying as well as under sulfate-reducing conditions pyridine was oxidized to carbon dioxide. Disappearance of nitrate and sulfate under anaerobic conditions was 79% and 85%, respectively, of the amount predicted from the stoichiometric equation for the complete transformation of pyridine.

Key words

Pyridine metabolism hydroxypyridines anaerobiosis denitrifying conditions sulfate-reducing conditions 


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Copyright information

© Birkhäuser Verlag 1991

Authors and Affiliations

  • J. -P. Kaiser
    • 1
  • J. -M. Bollag
    • 1
  1. 1.Laboratory of Soil BiochemistryThe Pennsylvania State UniversityUniversity ParkUSA

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