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Cyclic AMP level in red blood cells ofPlasmodium berghei-infectedMastomys natalensis

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Summary

The present report describes the changes in cyclic AMP level which occur upon parasitization of red cells byPlasmodium berghei. Parasitized erythrocytes were separated from the non-parasitized population by percoll density-gradient centrifugation. An increase in the cyclic AMP content of both non-parasitized and parasitized erythrocytes of infected animals compared with that of uninfected animals was observed. The patterns of physiological response to isoproterenol in normal, parasitized and non-parasitized erythrocytes were identical.

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Authors and Affiliations

  1. Division of Biochemistry, Faculty of Science, M. S. University of Baroda, 390 002, Baroda, India

    S. Khare

  2. Division of Biochemistry, Central Drug Research Institute, 226 001, Lucknow, India

    S. Ghatak

Authors
  1. S. Khare
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  2. S. Ghatak
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Khare, S., Ghatak, S. Cyclic AMP level in red blood cells ofPlasmodium berghei-infectedMastomys natalensis. Experientia 47, 236–238 (1991). https://doi.org/10.1007/BF01958145

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  • DOI: https://doi.org/10.1007/BF01958145

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