Abstract
A term, male neonate suddenly developed respiratory distress and severe cyanosis while undergoing exchange transfusion for hyperbilribinaemia. Transfusion-related acute lung injury was diagnosed. Because of persistent hypoxaemia despite aggressive treatment, two doses of surfactant were administered, resulting in marked improvement.
Similar content being viewed by others
Abbreviations
- ARDS :
-
adult respiratory distress syndrome
- RDS :
-
respiratory distress syndrome
- TRALI :
-
transfusion-related acute lung injury
References
Auten RL, Notter RH, Kendig JW, Davis JM, Shapiro DL (1991) Surfactant treatment of full-term newborns with respiratory failure. Pediatrics 87:101–107
Bui KC, Walther FJ, David-Cu R, Garg M, Warburton D (1992) Phospholipid and surfactant protein A concentrations in tracheal aspirates from infants requiring extracorporeal membrane oxygenation. J Pediatr 121:271–274
Holbrook PR, Taylor G, Pollack MM, Fields AI (1980) Adult respiratory distress syndrome in children. Pediatr Clin North Am 27:677–685
Khammash H, Perlman M, Wojtulewicz J, Dunn M (1993) Surfactant therapy in full-term neonates with severe respiratory failure. Pediatrics 92:135–139
Lachmann B (1989) Ammal models and clinical pilot studies of surfactant replacements in adult respiratory distress syndrome. Eur Respir J 2[Suppl 3]:98s-103s
Lewis JF, Jobe AH (1993) Surfactant and the adult respiratory distress syndrome. Am Rev Respir Dis 147:218–233
Lotze A, Whitsett JA, Kammerman LA, Ritter M, Taylor GA, Short BL (1990) Surfactant protein A concentrations in tracheal aspirate fluid from infants requiring extracorporeal membrane oxygenation. J Pediatr 116:435–440
Lotze A, Knight GR, Martin GR, et al. (1993) Improved pulmonary outcome after exogenous surfactant therapy for respiratory failure in term infants requiring extracorporeal membrane oxygenation. J Pediatr 122:261–268
Malouf M, Glanville (1993) Blood transfusion related adult respiratory distress syndrome. Anaesth Intens Care 21:44–49
Nosaka S, Sakai T, Yonekura M, Yoshikawa K (1990) Surfactant for adults with respiratory failure. Lancet 336:947–948
O'Connor JC, Strauss RG, Goeken NE, Knox LB (1988) A near-fatal reaction during granulocyte transfusion of a neonate. Transfusion 28:173–176
Pfenninger J, Gerber A, Tschappeler H, Zimmermann A (1982) Adult respiratory distress syndrome in children. J Pediatr 101:352–357
Popovsky MA, Abel MD, Moore SB (1983) Transfusion-related acute lung injury associated with passive transfer of antileukocyte antibodies. Am Rev Respir Dis 128:185–189
Popovsky MA, Chaplin HC Jr., Moore SB (1992) Transfusion-related acute lung injury: a neglected, serious complication of hemotherapy. Transfusion 32:589–592
Richman PS, Spragg RG, Robertson B, Merritt TA, Curstedt T (1989) The adult respiratory distress syndrome: first trials with surfactant replacement. Eur Respir J 2[Suppl 3]:109s-111s
Seeger W, Gunther A, Walmrath HD, Grimminger F, Lasch HG (1993) Alveolar surfactant and adult respiratory distress syndrome: Pathogenic role and therapeutic prospects. Clin Invest 71:177–190
Shinwell ES, Zmora E, Karplus M (1992) Surfactant therapy in respiratory failure other than respiratory distress syndrome in term and preterm infants. Pediatr Res 31:323A
Spragg RG, Gilliard N, Richman P, et al. (1994) Acute effects of a single dose of porcine surfactant on patients with the adult respiratory distress syndrome. Chest 105:195–202
Weg J, Reines H, Balk R, et al (1991) Safety and efficacy of an aerosolized surfactant (Exosurf) in human sepsis induced ARDS. Chest 100:137S
Wiedemann H, Baughman R, de Boisblanc B, et al (1992) A multicenter trial in human sepsis-induced ARDS of an aerosolized synthetic surfactant (Exosurf) (abstract). Am Rev Respir Dis 145:A184
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Wu, TJ., Teng, RJ. & Yau, KI.T. Transfusion-related acute lung injury treated with surfactant in a neonate. Eur J Pediatr 155, 589–591 (1996). https://doi.org/10.1007/BF01957910
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01957910