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Experientia

, Volume 28, Issue 12, pp 1515–1516 | Cite as

Partricin methyl ester, a semisynthetic polyene antibiotic

  • T. Bruzzese
  • I. Binda
  • A. Di Nardo
  • G. Ghielmetti
  • M. Riva
Article

Keywords

Gibberellic Acid Minimum Inhibitory Concentration Cellosolve Polyene Antibiotic Antifungal Antibiotic 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Zusammenfassung

Es wurde der Methylester von Partricin, eines polyenischen Antibiotikums, hergestellt. Das Produkt zeigte eine gesteigerte Aktivität gegen Hefen und eine verminderte Toxizität.

Literatur

  1. 1.
    H. Lechevalier, E. Borowski, J. O. Lampen andC. P. Schaffner, Antibiotics Chemother.11, 640 (1961).Google Scholar
  2. 2.
    C. P. Schaffner andE. Borowski, Antibiotics Chemother,11, 724 (1961).Google Scholar
  3. 3.
    Brit. Pat. Appl. No. 52,270 (3 November 1970).Google Scholar
  4. 4.
    W. Oroshnik, L. C. Vining, A. D. Mebane andW. A. Taber, Science21, 147 (1955).CrossRefGoogle Scholar
  5. 5.
    However, as in known natural polyenes, some similar substances may be present. SeeK. Hattori, H. Nakano, M. Seki andY. Hirata, J. Antibiotics, Ser. A9, 176 (1956).—F. Bohlmann, E. V. Dehmlow, H. J. Neuhahn, R. Brandt andB. Reinicke, Tetrahedron26, 2191 (1970).Google Scholar

Copyright information

© Birkhäuser Verlag 1972

Authors and Affiliations

  • T. Bruzzese
    • 1
  • I. Binda
    • 1
  • A. Di Nardo
    • 1
  • G. Ghielmetti
    • 1
  • M. Riva
    • 1
  1. 1.Research LaboratoriesSPA-Società Prodotti AntibioticiMilanoItaly

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