Gastrointestinal endoscopy in Henoch-Schönlein purpura
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Gastrointestinal (GI) endoscopy was performed in seven patients with Henoch-Schönlein purpura (HSP). In two patients there were no cutaneous lesions at the time of endoscopy, but inflammation of the duodenum, especially of the second part, led to suspicion of the disease. Upper GI endoscopy showed abnormalities in six of seven cases, and sigmoidoscopy in one of four cases. The changes were more marked in the second part of the duodenum rather than in the bulb or the stomach. The endoscopic findings included redness, swelling, petechiae or haemorrhage, erosions and ulceration of the mucosa. Histology of the mucosal biopsy specimens revealed non-specific inflammation with positive staining for IgA in the capillaries, but failed to show vasculitis. Upper GI endoscopy, including study of IgA, can be useful in the diagnosis of HSP. Colonoscopy is less helpful, especially if limited to the sigmoid colon.
Key wordsSchönlein-Henoch purpura Endoscopy Duodenitis IgA Peptic ulcer
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- 3.Beck IT (1985) Duodenitis. In: Berk JE, Haubrich WS, Vol. 2. 4th ed. WB Saunders, Philadelphia, pp 1403–1421Google Scholar
- 6.Feldt RW, Stickler GB (1962) The gastrointestinal manifestations of anaphylactoid purpura in children. Proc Mayo Clin 137:465–483Google Scholar
- 9.Kirschner BS (1991) Henoch-Schonlein purpura. In: Walker WA, Durie PR, Hamilton JR, Walker-Smith JA, Watkins JB (eds) Pediatric gastrointestinal disease. BC Decker, Philadelphia, pp 633–638Google Scholar