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Corpus cardiacum — a target for azadirachtin

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Summary

Azadirachtin A, an insect growth inhibitor derived from neem seed, when injected at a physiological dose, inhibits the hormonally controlled ovarian development inLocusta migratoria. Its tritiated dihydro derivative concentrates more in the corpus cardiacum than in the brain. Translocation and release of the neurosecretory proteins labeled with L-[35S]-cysteine in the corpus cardiacum is very poor in locusts under azadirachtin stress. It is concluded that azadirachtin may influence the release of trophic hormones from the corpus cardiacum leading to alterations in timing and titer of morphogenetic hormone pools.

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References

  1. Broughton, H., Ley, S. V., Slawin, A. M. Z., Williams, D. J., and Morgan, D. E., J. chem. Soc. chem. Commun.1986, 46.

  2. Rembold, H., Forster, H., Czoppelt, Ch., Rao, P. J., and Sieber, K.-P., in: Proc. 2nd Int. Neem Conf., Rauischholzhausen 1983, p. 153. Eds H. Schmutterer and K. R. S. Ascher. GTZ Eschborn 1984.

    Google Scholar 

  3. Rembold, H., Forster, H., and Czoppelt, Ch., in: Proc. 3rd Int. Neem Conf. Nairobi 1986, p. 149. Eds H. Schmutterer and K. R. S. Ascher. GTZ, Eschborn, 1987.

    Google Scholar 

  4. Rembold, H., Forster, H., and Sonnenbichler, J., Z. Naturforsch.42c (1987) 4.

    Article  Google Scholar 

  5. Butterworth, J. H., and Morgan, F. D., Chem. Commun.1968, 23.

  6. Butterworth, J. H., and Morgan, F. D., J. Insect. Physiol.17 (1971) 969.

    Article  CAS  Google Scholar 

  7. Ruscoe, C. N. E., Nature236 (1972) 159.

    Article  CAS  Google Scholar 

  8. Schmutterer, H., and Rembold, H., Z. angew. Ent.89 (1980) 179.

    Article  Google Scholar 

  9. Zanno, P. R., Miura, I., Nakanishi, K., and Elder, D. L., J. Am. chem. Soc.97 (1975) 1975.

    Article  CAS  PubMed  Google Scholar 

  10. Warthen, J. D. Jr, U. S. Dept. Agric., Agric. Rev. Man., ARM-NE4 (1979) 21.

  11. Sieber, K.-P., and Rembold, H., J. Insect Physiol.29 (1983) 523.

    Article  CAS  Google Scholar 

  12. Mordue, A. J., Evans, K. A., and Charlet, M., Comp. Biochem. Physiol.85C (1986) 297.

    CAS  Google Scholar 

  13. Rembold, H., Uhl, M., and Müller, T., in: Proc. 3rd Int. Neem Conf., Nairobi 1986, p. 289. Eds H. Schmutterer and K. R. S. Ascher. GTZ, Eschborn 1987.

    Google Scholar 

  14. Rembold, H., and Sieber, K.-P., Z. Naturforsch.36c (1981) 466.

    Article  CAS  Google Scholar 

  15. Garcia, E. S., and Rembold, H., J. Insect Physiol.30 (1984) 939.

    Article  CAS  Google Scholar 

  16. Rembold, H., Sharma, G. K., Czoppelt, C., and Schmutterer, H., Z. PflKrankh. Pflschutz87 (1980) 290.

    Google Scholar 

  17. Dorn, A., Rademacher, J. M., and Sehn, E., J. Insect Physiol.32 (1986) 231.

    Article  CAS  Google Scholar 

  18. Rembold, H., Müller, T., and Subrahmanyam, B., Z. Naturforsch.43c (1988) 903.

    Article  Google Scholar 

  19. Krogh, I. M., Acta zool.54 (1973) 73.

    Article  CAS  Google Scholar 

  20. Stone, J. V., Mordue, W., Batley, K. E. and Morris, H. R., Nature263 (1976) 207.

    Article  CAS  PubMed  Google Scholar 

  21. Siegert, K., Morgan, P., and Mordue, W., Biol. Chem. Hoppe-Seyler366 (1985) 723.

    Article  CAS  PubMed  Google Scholar 

  22. Rembold, H., Schlagintweit, B., and Ulrich, G. M., J. Insect Physiol.32 (1986) 91.

    Article  CAS  Google Scholar 

  23. Engelmann, F., Adv. Insects Physiol.14 (1979) 49.

    Article  CAS  Google Scholar 

  24. Hagedorn, H. H., and Kunkel, J. G., A. Rev. Ent.24 (1979) 475.

    Article  CAS  Google Scholar 

  25. Sloper, G. C., Nature179 (1957) 148.

    Article  CAS  PubMed  Google Scholar 

  26. Mordue, A. J., and Highnam, K. C., Gen. comp. Endocr.20 (1973) 351.

    Article  CAS  PubMed  Google Scholar 

  27. McCaffery, A. R., and Highnam, K. C., Gen. comp. Endocr.25 (1975) 358.

    Article  CAS  PubMed  Google Scholar 

  28. Subrahmanyam, B., and Rembold, H., Cell Tissue Res. (1989) in press.

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Authors and Affiliations

  1. Max-Planck-Institute for Biochemistry, D-8033, Martinsried, Federal Republic of Germany

    H. Rembold, B. Subrahmanyam & T. Müller

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  1. H. Rembold
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  2. B. Subrahmanyam
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  3. T. Müller
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Rembold, H., Subrahmanyam, B. & Müller, T. Corpus cardiacum — a target for azadirachtin. Experientia 45, 361–363 (1989). https://doi.org/10.1007/BF01957478

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  • DOI: https://doi.org/10.1007/BF01957478

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