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Latent iron deficiency alters gamma-aminobutyric acid and glutamate metabolism in rat brain

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Summary

A diet containing 18–20 mg iron/kg to young weaned rats for 8 weeks altered the metabolism of gamma-aminobutyric acid and glutamate in the central nervous system without affecting blood hemoglobin. Subsequent rehabilitation with 390 mg iron/kg diet for 2 weeks normalized these changes.

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Authors and Affiliations

  1. Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India

    A. Shukla & K. N. Agarwal

  2. Neuroscience Laboratory Building, The University of Michigan, 48104, Ann Arbor, Michigan, USA

    G. S. Shukla

  3. Neuroscience Laboratory Building, The University of Michigan, 1103 East Huron, 48104-1687, Ann Arbor, MI, USA

    A. Shukla

Authors
  1. A. Shukla
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  2. K. N. Agarwal
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  3. G. S. Shukla
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Shukla, A., Agarwal, K.N. & Shukla, G.S. Latent iron deficiency alters gamma-aminobutyric acid and glutamate metabolism in rat brain. Experientia 45, 343–345 (1989). https://doi.org/10.1007/BF01957472

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  • DOI: https://doi.org/10.1007/BF01957472

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