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Prothymosin alpha is not a nuclear polypeptide

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Summary

Using a radioimmunoassay for the NH2-terminus of prothymosin alpha, the crossreactive material was measured in subcellular fractions of calf thymus and liver. No significant amount of crossreactive material was found in the nucleus. This provides experimental evidence against a recent hypothesis, based on structural evidence, that prothymosin alpha is a nuclear polypeptide.

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Authors and Affiliations

  1. Zoological Laboratory, Faculty of Sciences, University of Athens, GR-15784, Athens, Greece

    O. E. Tsitsiloni, P. P. Yialouris & A. A. Haritos

  2. Department of Biology, National Research Center of Natural Sciences ‘Demokritos’, Aghia Paraskevi, GR 153 10, Athens, Greece

    K. Sekeri-Pataryas

Authors
  1. O. E. Tsitsiloni
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  2. P. P. Yialouris
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  3. K. Sekeri-Pataryas
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  4. A. A. Haritos
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Tsitsiloni, O.E., Yialouris, P.P., Sekeri-Pataryas, K. et al. Prothymosin alpha is not a nuclear polypeptide. Experientia 45, 332–334 (1989). https://doi.org/10.1007/BF01957467

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  • DOI: https://doi.org/10.1007/BF01957467

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