Experientia

, Volume 45, Issue 4, pp 325–327 | Cite as

Fungitoxicity ofm-fluorophenylalanine-containing peptides towardsPythium ultimum

  • D. H. Young
  • R. J. Mehta
Article

Summary

The tripeptide L-m-fluorophenylalanyl-L-alanyl-L-alanine was much more fungitoxic towardsPythium ultimum than the dipeptide L-m-fluorophenylalanyl-L-alanine orm-fluorophenylalanine. The fungitoxicity of the tripeptide was reduced by L-alanyl peptides and phenylalanine, but not by other amino acids. In contrast, the fungitoxicity ofm-fluorophenylalanine was unaffected by peptides, and was antagonized by several amino acids. These results suggest the effective delivery ofm-fluorophenylalanine into the cell by a tripeptide carrier.

Key words

Amino acid transport fluorophenylalanine peptide transport Pythium ultimum 

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Copyright information

© Birkhäuser Verlag Basel 1989

Authors and Affiliations

  • D. H. Young
    • 1
  • R. J. Mehta
    • 1
  1. 1.Research LaboratoriesRohm and Haas Co.Spring HouseUSA

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