European Journal of Pediatrics

, Volume 152, Issue 12, pp 998–1000 | Cite as

Effect of interleukin 2 on intractable herpes virus infection and chronic eczematoid dermatitis in a patient with Wiskott-Aldrich syndrome

  • H. Azuma
  • H. Sakata
  • M. Saijyou
  • A. Okuno


Recombinant interleukin 2 (rIL2) was administered to a patient with Wiskott-Aldrich syndrome for the treatment of an intractabel facial herpetiforme lesion. This treatment appeared to be effective in suppressing the virus activity. At the same time, a transient improvement of the chronic eczematoid dermatitis was observed. During rIL2 administration, the CD3+ and CD4+ subsets of peripheral blood lymphocytes increased in number. These changes might play an important role in the induction of anti-viral immunity and in the improvement of dermatits.

Key words

Recombinant IL2 Wiskott-Aldrich syndrome Atopic dermatitis Herpes virus infection 



recombinant Interleukin 2


Wiskott-Aldrich syndrome


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Copyright information

© Springer-Verlag 1993

Authors and Affiliations

  • H. Azuma
    • 1
  • H. Sakata
    • 1
  • M. Saijyou
    • 1
  • A. Okuno
    • 1
  1. 1.Department of PaediatricsAsahikawa Medical CollegeAsahikawa, Hokkaido 078Japan

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