References
Cremer R, Horneff G, Wahn V (1995) Schwere und rezidivierende Meningo-kokkeninfectionen bei 2 Geschwistern mit Fehlen des Komplementfaktors 6. Monatsschr Kinderheilkd 143:264–267
Nürnberger W, Pietsch H, Willers R, et al (1989) Deficiency of the eighth component of complement. Evidence for linkage of C8α-γ pattern with C8β deficiency in sera of twelve patients. Scand J Immunol 30:45–49
Nürnberger W, Pietsch H, Kobler P, et al (1989) Rezidivierende Meningitiden bei familiärem Defekt der β-Untereinheit der achten Komplementkomponente. Dtsch Med Wochenschr 114: 989–992
Nürnberger W, Pietsch, H, Seger R, et al (1989) Familial deficiency of the seventh component of complement associated with recurrent meningococcal infections. Eur J Pediatr 148:758–760
Pietsch H, Raab K, Lalyko K, Wahn V (1993) Homozygoter C 7 Defekt in einer deutschen Familie. Monatsschr Kinderheilkd 141:412–415
Platonov AE, Beloborodov VB, Pavlova LI, et al (1995) Vaccination of patients deficient in a late complement component with tetravalent meningococcal capsular polysaccharide vaccine. Clin Exp Immunol 100:32–39
Wahn V, Müller W, Rieger C, Rother U (1987) Persistently circulating C3 nephritic factor (C3-Nef)-stabilized alternative pathway convertase (C3 CoF) in serum of an 11-year-old girl with meningococcal septicemia — simultaneous occurence with free C3 NeF. Pediatr Res 22:123–129
References
Fijen CAP (1995) Meningococcal disease and complement deficiencies in the Netherlands. Thesis, University of Amsterdam, Amsterdam, The Netherlands
Fijen CAP, Kuijper EJ, Hannema AJ, Sjoholm AG, Putten JPM van (1989) Complement deficiencies in patients over ten years old with meningococcal disease due to uncommon serogroups. Lancet II:585–589
Mayer MM (1961) Complement and complement fixation. In: Kabat EA, Mayer MM (eds) Experimental immunochemistry, 2nd edn. Springfield, Il: Charles C. Thomas, pp 133–240
Nilsson UR, Nilsson B (1984) Simplified assays of hemolytic activity of the classical and alternative complement pathway. J Immunol Methods 72:49–59
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Cremer, R., Wahn, V., Fijen, C. et al. Deficiency of late complement components in patients with severe and recurrent meningococcal infections. Eur J Pediatr 155, 723–724 (1996). https://doi.org/10.1007/BF01957164
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DOI: https://doi.org/10.1007/BF01957164