, Volume 38, Issue 12, pp 1470–1471 | Cite as

Contraction of the large conductance coronary artery produced by acetylcholine in the mini pig

  • M. Nakazawa
  • K. Takeda
  • Y. Nakagawa
  • S. Imai
Short Communications Pharmacology, Toxicology


In the mini pig, acetylcholine reduced the coronary blood flow and constricted the large coronary artery. These effects were abolished by atropine, but not by phentolamine, suggesting that cholinergic mechanisms may be involved in coronary artery vasoconstriction.


Blood Flow Coronary Artery Acetylcholine Atropine Coronary Blood Flow 
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Copyright information

© Birkhäuser Verlag 1982

Authors and Affiliations

  • M. Nakazawa
    • 1
  • K. Takeda
    • 1
  • Y. Nakagawa
    • 1
  • S. Imai
    • 1
  1. 1.Department of PharmacologyNiigata University School of MedicineNiigataJapan

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