, Volume 42, Issue 6, pp 627–628 | Cite as

New phytotoxic butenolides produced bySeiridium cardinale, the pathogen of cypress canker disease

  • L. Sparapano
  • A. Evidente
  • A. Ballio
  • A. Graniti
  • G. Randazzo
Short Communications


Two new butenolides, seiridin andiso-seiridin, were isolated from culture filtrates ofSeiridium cardinale, the pathogen of cypress canker, a destructive disease ofCupressus and relatedConiferae These metabolites were characterized as 3-methyl-4-(2-hydroxyheptyl)-2(5H)-furanone and its 4-(3-hydroxyheptyl) isomer, respectively. Chlorotic, and necrotic symptoms were produced on leaves of either host or non-host test plants by absorption of 0.3 mg/ml solutions of either compound. These also showed antibacterial activity.

Key words

Seiridium cardinale cypress canker seiridin iso-seiridin butenolides phytotoxins antibiotics 


  1. 2.
    Barthelet, J., and Vinot, M., Ann. Epiphyt.10 (1944) 18.Google Scholar
  2. 3.
    Wagener, W.W., J. agric. Res.58 (1939) 1.Google Scholar
  3. 4.
    Grasso V., and Raddi, P. (Eds), Seminario: Il Cipresso: malattie e difesa, P. 251. CEE-AGRIMED, Firenze 1979.Google Scholar
  4. 5.
    Graniti, A., EPPO Bull.15 (1985) (in press).Google Scholar
  5. 6.
    Capineri, R., Marchi, P., Trilli, A., and Tonolo, A., Phytopath. medit.10 (1972) 172.Google Scholar
  6. 7.
    Lorenzini, G., and Triolo, E., Phytopath. medit.17 (1978) 96.Google Scholar
  7. 8.
    Triolo, E., and Lorenzini, G., Riv. Patol. veg.16 (1980) 87.Google Scholar
  8. 9.
    Sparapano, L., Graniti, A., and Gimenez Verdu, I., Phytopath. medit.24 (1985) (in press).Google Scholar
  9. 10.
    Rao, Y.S., Chem. Rev.76 (1976) 625.Google Scholar
  10. 11.
    Turner, W.B., and Aldridge, D.C., Fungal metabolites II, p. 631. Academic Press, London 1983.Google Scholar
  11. 12.
    Edwards, R.L., and Whalley, A.J.S., J. chem. Soc., Perkin I (1979) 803.Google Scholar

Copyright information

© Birkhäuser Verlag 1986

Authors and Affiliations

  • L. Sparapano
    • 1
  • A. Evidente
    • 2
  • A. Ballio
    • 3
  • A. Graniti
    • 1
  • G. Randazzo
    • 2
  1. 1.Dipartimento di Patologia vegetaleUniversity of BariBari(Italy)
  2. 2.Dipartimento di Chimica organica e biologicaUniversity of NaplesNaples(Italy)
  3. 3.Istituto di Chimica biologicaLa Sapienza' University of RomeRome(Italy)

Personalised recommendations