European Journal of Pediatrics

, Volume 150, Issue 4, pp 274–276 | Cite as

Clinical usefulness of high intensity green light phototherapy in the treatment of neonatal jaundice

  • M. Amato
  • D. Inaebnit


Two matched groups of term newborn infants with idiopathic jaundice were subjected to intensive double direction green or blue light phototherapy (PT). The efficacy of treatment was expressed as rate of decline of serum bilirubin concentration after 6, 12 and 24 h of light exposure. More rapid response was obtained using conventional blue lamps (Philips TL/20W/52) than green lamps (Sylvania F20T12/G). Whole duration of PT was significantly shorter using blue lamps (P<0.05). However, less postphototherapy rebound was observed in babies treated with green light PT. It can be concluded that green light PT is useful but not preferable to blue light PT for clinical use in the treatment of neonatal jaundice.

Key words

Neonatal jaundice Term infants Green light phototherapy 





Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Amato M, Carasso A, Von Muralt G (1983) Photothérapie intensive avec une double lampe bleue dans le traitement de l'hyperbilirubinémie néonatale. Helv Paediatr Acta 38:467–473PubMedGoogle Scholar
  2. 2.
    Amato M, Von Muralt G, Auf der Maur P (1985) Double direction phototherapy and light-induced genetic abnormalities in human lymphocytes. Helv Paediatr Acta 40:285–291PubMedGoogle Scholar
  3. 3.
    Ayyash H, Hadjigeorgiou E, Sofatzis J, Chatziioannou A, Nicolopoulos D, Sideris E (1987) Green light phototherapy in newborn infants with ABO hemolytic disease. J Pediatr 111: 882–887PubMedGoogle Scholar
  4. 4.
    Ayyash H, Hadjigeorgiou E, Sofatzis J, Dellagramaticas H, Sideris E (1987) Green versus blue light phototherapy for neonates with hyperbilirubinemia: a controlled study. Arch Dis Child 62:843–845PubMedGoogle Scholar
  5. 5.
    Ballard J, Kazmaier K, Driver M (1977) Simplified assessment of gestational age. Pediatr Res 11:374Google Scholar
  6. 6.
    Brown A, Mc Donagh A (1980) Phototherapy for neonatal hyperbilirubinemia: efficacy, mechanism and toxicity. Adv Pediatr 3:341–389Google Scholar
  7. 7.
    Ebbesen F (1979) Superiority of intensive phototherapy-blue double light — in Rhesus haemolytic disease. Eur J Pediatr 130:279–284PubMedGoogle Scholar
  8. 8.
    Ennever J, Mc Donagh A, Speck W (1983) Phototherapy for neonatal jaundice: optimal wavelengths of light. J Pediatr 103:295–299PubMedGoogle Scholar
  9. 9.
    Ennever J, Knox I, Denne S, Speck W (1985) Phototherapy for neonatal jaundice: in vivo clearance of bilirubin photoproducts. Pediatr Res 19:205–209PubMedGoogle Scholar
  10. 10.
    Ennever J, Knox I, Speck W (1986) Differences in bilirubin isomer composition in infants treated with green and white light phototherapy. J Pediatr 109:119–121PubMedGoogle Scholar
  11. 11.
    Hegyi T, Graff M, Zapanta V, Hiatt M, Sisson T (1986) Transcutaneous bilirubinometry. Dermal bilirubin kinetics under green and blue light phototherapy. Am J Dis Child 140:994–997PubMedGoogle Scholar
  12. 12.
    McGinty L, Flower R (1982) Visible light mutagenesis in Escherichia Coli. Mutat Res 95:171–181PubMedGoogle Scholar
  13. 13.
    Romagnoli C, Marrocco G, De Carolis M, Zecca E, Tortorolo G (1988) Phototherapy for hyperbilirubinemia in preterm infants: green versus blue or white light. J Pediatr 112:476–478PubMedGoogle Scholar
  14. 14.
    Sbrana G, Donzelli G, Vecchi C (1987) Phototherapy in the management of neonatal hyperbilirubinemia: efficacy with light sources emitting more than 500 nanometer. Pediatrics 80:395–398PubMedGoogle Scholar
  15. 15.
    Sisson T, Kendall N, Davies R, Berger D (1970) Factors influencing the effectiveness of phototherapy in neonatal hyperbilirubinemia. Birth Defects 6:100–104PubMedGoogle Scholar
  16. 16.
    Speck W, Chen C, Rosenkranz H (1975) In vitro studies of effects of light and Riboflavin on DNA and HeLa cells. Pediatr Res 9:150–153PubMedGoogle Scholar
  17. 17.
    Tan KL (1975) Comparison of the effectiveness of single direction and double direction phototherapy for neonatal jaundice. Pediatrics 56:550–553PubMedGoogle Scholar
  18. 18.
    Tan KL (1977) The nature of the dose-response relationship of phototherapy for neonatal hyperbilirubinemia. J Pediatr 90: 448–452PubMedGoogle Scholar
  19. 19.
    Tan KL (1989) Efficacy of fluorescent daylight, blue and green lamps in the management of nonhemolytic hyperbilirubinemia. J Pediatr 114:132–137PubMedGoogle Scholar
  20. 20.
    Vecchi C, Donzelli GP, Migliorini MG, Sbrana G (1983) Green light in phototherapy. Pediatr Res 17:461–463PubMedGoogle Scholar
  21. 21.
    Vecchi C, Donzelli GP, Sbrana G, Pratesi R (1986) Phototherapy for neonatal jaundice: clinical equivalence of fluorescent green and “special” blue lamps. J Pediatr 108:452–456PubMedGoogle Scholar

Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • M. Amato
    • 1
  • D. Inaebnit
    • 1
  1. 1.Division of Neonatology, Department of Obstetrics and GynaecologyUniversity of Berne and Children's HospitalAarauSwitzerland

Personalised recommendations