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Effect of heat-labile enterotoxin (LT) produced byEscherichia coli on in vitro cell proliferation

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Summary

Filtrates fromE. coli H10407 cultures, giving a positive response for heat-labile enterotoxin (LT) in the Y-1 cell test, show an inhibitory activity both on3H-thymidine uptake by Ehrlich ascites cells and on granulocytic-macrophagic precursors (CFU-C) in murine bone marrow.

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Authors and Affiliations

  1. Department of Microbiology, Faculty of Medicine, University of Milan, 31, Mangiagalli, I-20133, Milan, Italy

    A. Pessina, Maria Grazia Neri & A. Muschiato

  2. Department of Pathology, Hospital of Desio, Desio, I-20033, Milan, Italy

    A. Pessina, Maria Grazia Neri & A. Muschiato

Authors
  1. A. Pessina
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  2. Maria Grazia Neri
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  3. A. Muschiato
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Additional information

Acknowledgments. We gratefully acknowledge the expert technical assistance of L. Basso and A. Gerosa of Department of Pathology, Hospital of Desio.

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Pessina, A., Neri, M.G. & Muschiato, A. Effect of heat-labile enterotoxin (LT) produced byEscherichia coli on in vitro cell proliferation. Experientia 38, 1056–1057 (1982). https://doi.org/10.1007/BF01955364

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  • DOI: https://doi.org/10.1007/BF01955364

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