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Teratogenic effects of azaserine in the Syrian golden hamster

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Summary

Azaserine is a potent pancreatic carcinogen in the rat, but not in the Syrian golden hamster. The present study shows, however, that the hamster shares with the rat susceptibility to the embryotoxic and teratogenic effects of this drug.

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Authors and Affiliations

  1. Department of Pharmacology and Toxicology, and Department of Anatomy, Dartmouth Medical School, 03756, Hanover, New Hampshire, USA

    B. D. Roebuck & S. J. Carpenter

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  1. B. D. Roebuck
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  2. S. J. Carpenter
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Additional information

This work was supported in part by USPHS grant HD-09585 (SJC) and CA-26594 (BDR).

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Roebuck, B.D., Carpenter, S.J. Teratogenic effects of azaserine in the Syrian golden hamster. Experientia 39, 324–326 (1983). https://doi.org/10.1007/BF01955329

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