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Tryptophan and neutral amino acid concentrations in serum of rats after salmon calcitonin injection

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Summary

After a single injection of salmon calcitonin (2 MRC units/kg b.wt) marked decreases in both calcium and neutral amino acids in rat serum were observed. In turn, free tryptophan in serum and serotonin (5-hydroxytryptamine) in the whole brain were greatly enhanced during the initial period.

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References

  1. Knott, P. J., and Gurzon, G., Nature, Lond.239 (1972) 452.

    Article  CAS  PubMed  Google Scholar 

  2. Tagliamonte, A., Biggio, G., Vargiu, L., and Gessa, G. L., Life Sci.12 (1973) 277.

    Article  CAS  Google Scholar 

  3. Nakhla, A. M., and Nandi Majumbar, A. P., Biochem. J.170 (1978) 445.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Fernstrom, J. D., and Wurtman, R. J., Science178 (1972) 414.

    Article  CAS  PubMed  Google Scholar 

  5. Kennet, G. A., and Joseph, M. H., Neuropharmacology20 (1981) 39.

    Article  Google Scholar 

  6. Bryan Brewer, H., Keutmann, H. T., Potts, J. T., Reisfeld, R. A., Schlueter, R., and Munson, P. L., J. biol. Chem.243 (1968) 5739.

    Article  Google Scholar 

  7. Rubin, M., in: The transfer of calcium and strontium across biological membranes, p. 39. Ed. R. H. Wasserman. Academic Press, New York 1963.

    Google Scholar 

  8. Denkla, W. D., and Dewey, H. K., J. Lab. clin. Med.69 (1967) 160.

    Google Scholar 

  9. Lehman, J., Scand. J. clin. Lab. Invest.28 (1971) 49.

    Article  Google Scholar 

  10. Bloxam, D. L., and Warren, Analyt. Biochem.60 (1974) 621.

    Article  CAS  PubMed  Google Scholar 

  11. Bourgoin, S., Faivre-Bauman, A., Benda, P., Glowinski, J., and Hamon, M., J. Neurochem.23 (1972) 319.

    Article  Google Scholar 

  12. Gaitonde, M. K., Evans, G., and Hartman, M. K., Analyt. Biochem.92 (1979) 338.

    Article  CAS  PubMed  Google Scholar 

  13. Moore, S., and Stein, W. H., J. biol. Chem.192 (1951) 663.

    Article  CAS  PubMed  Google Scholar 

  14. Curzon, G., and Green, A. R., Br. J. Pharmac.39 (1970) 653.

    Article  CAS  Google Scholar 

  15. Fujita, T., Orimo H., and Yoshikawa, M., Endocrinology78 (1966) 1082.

    Article  CAS  PubMed  Google Scholar 

  16. Erikson, T., Carlsson, A., Liljequist, S., Hagman, M., and Jagenburg, R., J. Pharm. Pharmac.32 (1980) 512.

    Article  Google Scholar 

  17. Hamon, S., Ph. D. thesis. University, Paris VII, Paris 1977.

  18. Yuwiler, A., Simon, M., Bennett, B., Plotkin, S., Wallace, R., Brammer, G., and Ulrich, R., Endocr. Exp.12 (1978) 21.

    CAS  Google Scholar 

  19. Miller, M., and Resnick, O., Exp. Neurol.67 (1980) 298.

    Article  CAS  PubMed  Google Scholar 

  20. Fernstrom, J. D., and Wurtman, R. J., Metabolism21 (1972) 337.

    Article  CAS  PubMed  Google Scholar 

  21. Weil-Fugazza, J., Godefroy, F., Coudert, D., and Besson, J. M., Pain9 (1980) 319.

    Article  CAS  PubMed  Google Scholar 

  22. Curzon, G., and Knott, P. J., Br. J. Pharmac.50 (1974) 197.

    Article  CAS  Google Scholar 

  23. Wu, S. Y., and Rosenthal, H. L., Proc. Soc. exp. Biol. Med.122 (1966) 414.

    Article  CAS  PubMed  Google Scholar 

  24. Yuwiler, A., Geller, E., and Chapiro, S., Can. J. Physiol. Pharmac.47 (1969) 317.

    Article  CAS  Google Scholar 

  25. McMenamey, H., and Oncley, J. L., J. biol. Chem.233 (1958) 1436.

    Article  Google Scholar 

  26. Horwitt, M. K., Harvey, C. C., and Dahm, C. H., Am. J. clin. Nutr.28 (1975) 408.

    Article  Google Scholar 

  27. Fernstrom, J. D., Fedn. Proc.35 (1976) 1151.

    CAS  Google Scholar 

  28. Friedman, P. A., Kappelman, A. M., and Kaufman, S., J. biol. Chem.247 (1972) 4165.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Unité 53, INSERM, Rue Camille Saint-Saëns, F-33077, Bordeaux Cedex, France

    B. Dupuy, E. Peuchant, S. Vitiello, R. Jensen, A. Baghdiantz & P. Blanquet

Authors
  1. B. Dupuy
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  2. E. Peuchant
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  3. S. Vitiello
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  4. R. Jensen
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  5. A. Baghdiantz
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  6. P. Blanquet
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Additional information

We thank Dr Desaulles and Dr Scholer of Ciba-Geigy laboratories for the gift of M-sulfoxide calcitonin, an inactive derivate of the hormone and Dr Azria of Sandoz SA for the gift of synthetic salmon calcitonin.

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Dupuy, B., Peuchant, E., Vitiello, S. et al. Tryptophan and neutral amino acid concentrations in serum of rats after salmon calcitonin injection. Experientia 39, 294–296 (1983). https://doi.org/10.1007/BF01955312

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  • DOI: https://doi.org/10.1007/BF01955312

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