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Photobiological activity of 5,7-dimethoxycoumarin

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Summary

Some biological properties of 5,7-dimethoxycoumarin (DMC) include dark induced frameshift mutagenesis in bacteria, lethal photosensitization and the formation of sister chromatid exchanges in Chinese hamster cells. The number of sister chromatid exchanges per unit of cell lethality produced by DMC is almost the same as observed with 5-methoxypsoralen.

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References

  1. Song, P.-S. and Tapley, Jr, K. J., Photochem. Photobiol.29 (1979) 1177.

    Article  CAS  PubMed  Google Scholar 

  2. Parsons, B. J., Photochem. Photobiol.32 (1980) 813.

    Article  CAS  PubMed  Google Scholar 

  3. Cahn, J., Forlot, P., Grupper, C., Meybeck, A., and Urbach, F., eds., Psoralens in Cosmetics and Dermatology, Pergamon Press, Paris 1981.

    Google Scholar 

  4. Beaumont, P. C., Land, E. J., Navaratnam, S., Parsons, B. J., and Phillips, G. O., Biochim. biophys. Acta608 (1980) 182.

    Article  CAS  PubMed  Google Scholar 

  5. Sherman, W. V., and Grossweiner, L. I., Photochem. Photobiol.34 (1981) 579.

    Article  CAS  PubMed  Google Scholar 

  6. Dall'acqua, F., Marciani, S., and Rodighiero, G., FEBS Lett.9 (1970) 121.

    Article  CAS  PubMed  Google Scholar 

  7. Dall'acqua, F., Marciani, S., Ciavatta, L., and Rodighiero, G., Z. Naturforsch.B26 (1971) 561.

    Article  Google Scholar 

  8. Cole, R. S., Biochim. biophys. Acta217 (1970) 30.

    Article  CAS  PubMed  Google Scholar 

  9. Averbeck, D., and Moustacchi, E., Photochem. Photobiol.31 (1980) 475.

    Article  CAS  Google Scholar 

  10. Belogurov, A. A., and Zavilgelsky, G. B., Mutation Res.84 (1981) 11.

    Article  CAS  PubMed  Google Scholar 

  11. Parrish, J. A., Fitzpatrick, T. B., Tanenbaum, L., and Pathak, M. A., N. Engl. J. Med.291 (1974) 1207.

    Article  CAS  PubMed  Google Scholar 

  12. Melski, J. W., Tanenbaum, L., Parrish, J. A., Fitzpatrick, T. B., and Bleich, H. L., J. invest. Derm.68 (1977) 328.

    Article  CAS  PubMed  Google Scholar 

  13. Tronnier, H., and Lohning, R., Castellania2 (1974) 267; in: Photochemotherapy, Basic Technique and Side Effects, p. 71. Ed. E. G. Jung, Schattauer Verlag, Stuttgart 1976.

    Google Scholar 

  14. Roenigk, Jr, H. H., in: Psoralens in Cosmetics and Dermatology, p. 211. Eds, J. Cahn et al. Pergamon Press, Paris 1981.

    Google Scholar 

  15. Ashwood-Smith, M. J., and Grant, E. L., B. med. J.1 (1979) 342.

    Article  Google Scholar 

  16. Ashwood-Smith, M. J., Grant, E. L., Heddle, J. A., and Friedman, G. B., Mutation Res.43 (1977) 377.

    Article  CAS  PubMed  Google Scholar 

  17. Stern, R. S., Thibodeau, L. A., Kleinerman, R. A., Parrish, J. A., and Fitzpatrick, T. B., N. Engl. J. Med.300 (1979) 809.

    Article  CAS  PubMed  Google Scholar 

  18. Stern, R. S., in: Psoralens in Cosmetics and Dermatology, p. 203. Eds J. Cahn et al. Pergamon Press, Paris 1981.

    Google Scholar 

  19. Averbeck, D., Moustacchi, E., and Bisagni, E., Biochim. biophys. Acta518 (1978) 464.

    Article  CAS  PubMed  Google Scholar 

  20. Ou, C.-N., Song, P.-S., Harter, M. L. and Felkner, I. C., Photochem. Photobiol.24 (1976) 487.

    Article  CAS  PubMed  Google Scholar 

  21. Harter, M. L., Felkner, I. C., and Song, P.-S., Photochem. Photobiol.24 (1976) 491.

    Article  CAS  PubMed  Google Scholar 

  22. Stanley, W. L. and Vannier, S. H., J. Am. chem. Soc.79 (1957) 3488.

    Article  CAS  Google Scholar 

  23. Stanley, W. L., and Vannier, S. H., Phytochemistry,6 (1967) 585.

    Article  CAS  Google Scholar 

  24. Latz, H. W., and Madsen, B. C., Analyt. Chem.41 (1969) 1180.

    Article  CAS  Google Scholar 

  25. Ashwood-Smith, M. J., Poulton G. A., Barker, M., and Mildenberger, M., Nature, Lond.285 (1980) 407.

    Article  CAS  PubMed  Google Scholar 

  26. Bridges, B. A., and Mottershead, R. P., Mutation Res.44 (1977) 305.

    Article  CAS  PubMed  Google Scholar 

  27. Ashwood-Smith, M. J., Mutation Res.58 (1978) 23.

    Article  CAS  PubMed  Google Scholar 

  28. Ashwood-Smith, M. J., and Grant, E. L., Experientia33 (1977) 384.

    Article  CAS  PubMed  Google Scholar 

  29. Perry, P., and Wolff, S., Nature, Lond.251 (1974) 156.

    Article  CAS  PubMed  Google Scholar 

  30. Ashwood-Smith, M. J., Natarajan, A. T., and Poulton, G. A., in: Psoralens in Cosmetics and Dermatology, p. 117. Eds J. Cahn et al. Pergamon Press, Paris 1981.

    Google Scholar 

  31. Ou, C.-N., Tsai, C.-H., Tapley, Jr, K. J., and Song, P.-S., Biochemistry17 (1978) 1047.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Biology and Department of Chemistry, University of Victoria, V8W2Y2, Victoria, British Columbia, Canada

    M. J. Ashwood-Smith, G. A. Poulton & M. Liu

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  1. M. J. Ashwood-Smith
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  2. G. A. Poulton
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  3. M. Liu
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Ashwood-Smith, M.J., Poulton, G.A. & Liu, M. Photobiological activity of 5,7-dimethoxycoumarin. Experientia 39, 262–264 (1983). https://doi.org/10.1007/BF01955294

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