European Journal of Pediatrics

, Volume 155, Issue 5, pp 422–423 | Cite as

Dextrometorphan in molybdenum cofactor deficiency

  • Gerhard Kurlemann
  • Ottfried Debus
  • Gerhard Schuierer
Letters To The Editors

Keywords

Public Health Molybdenum Molybdenum Cofactor Molybdenum Cofactor Deficiency 

Abbreviations

DM

dextromethorphan

MCD

molybdenum cofactor deficiency

NMDA

N-methyl-D-aspartate

References

  1. 1.
    Ferkany JW, Borosky SA, Clissold DB, Pontecorvo J (1988) Dextromethorphan inhibits NMDA-induced convulsion. Eur J Pharmacology 151: 151–154Google Scholar
  2. 2.
    Johnson JL, Wadman SK (1988) Molydenum cofactor deficiency. In: Scriver CR, Beaudet AL, Sly WS, Valle D (eds) The metabolic basis of inherited disease, 6th edn. McGraw-Hill, New York, pp 1463–1475Google Scholar
  3. 3.
    Olney JW, Misra CH, Gubareff T de (1975) Cysteine-S-sulfate: brain damaging metabolite in sulfite oxidase deficiency. J Neuropathol Exp Neurol 34: 167–177Google Scholar
  4. 4.
    Schmitt B, Steinmann B, Gitzelmann R, Thun-Hohenstein L, Mascher H, Dumermuth G (1993) Nonketotic hyperglycinemia: clinical and electrophysiologic effects of dextromethorphan, an antagonist of the NMDA receptor. Neurology 43: 421–424Google Scholar
  5. 5.
    Schuierer G, Kurlemann G, Bick U, Stephani U (1995) Molybdenum cofactor deficiency: CT and MR findings. Neuropediatrics 26: 51–54Google Scholar

Copyright information

© Springer-Verlag 1996

Authors and Affiliations

  • Gerhard Kurlemann
    • 1
  • Ottfried Debus
    • 1
  • Gerhard Schuierer
    • 2
  1. 1.Bereich NeuropädiatrieUniversitäts-Kinderklinik MünsterMünsterGermany
  2. 2.Institut für klinische RadiologieUniversität MünsterMünsterGermany

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