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Effect of sodium butyrate in combination with X0irradiation, chemotherapeutic and cyclic AMP stimulating agents on neuroblastoma cells in culture

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Summary

Sodium butyrate, X-irradiation, chemotherapeutic agents and cyclic AMP-stimulating agents caused reduction in the cell number (due to cell death and reduction in cell division) when added individually to mouse neuroblastoma cells in culture. However, the combination of sodium butyrate with X-irradiation, chemotherapeutic and cyclic AMP-stimulating agents produced a greater reduction in the cell number than that produced by the individual agents.

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Literatur

  1. This work was supported in part by National Institute of Health. We thank Marianne Gaschler for her technical help.

  2. K.N. Prasad and P.K. Sinha, In Vitro12 (1975).

  3. P.H. Fishman, R.M. Bradley and R.C. Henneberry, Archs. Biochem. Biophys.172, 618 (1976).

    Article  CAS  Google Scholar 

  4. A. Leder and P. Leder, Cell5, 319 (1975).

    Article  CAS  PubMed  Google Scholar 

  5. N.K. Ghosh, S.E. Deutsch and M.J. Griffin, J. Cell Physiol.86, 663 (1975).

    Article  CAS  PubMed  Google Scholar 

  6. K.N. Prasad and A.W. Hsie, Nature New Biol.233, 141 (1971).

    Article  CAS  PubMed  Google Scholar 

  7. K.N. Prasad, B. Mandal, J.C. Waymire, G.J. Lees, A. Vernadakis and N. Weiner, Nature New Biol.241, 117 (1973).

    Article  CAS  PubMed  Google Scholar 

  8. K.N. Prasad, Nature234, 471 (1971).

    Article  CAS  PubMed  Google Scholar 

  9. O.H. Lowry, N.J. Rosebrough, A.L. Farr and R.J. Randall, J. biol. Chem.193, 265 (1951).

    Article  CAS  PubMed  Google Scholar 

  10. K.N. Prasad, Biol. Rev.50, 129 (1975).

    Article  CAS  PubMed  Google Scholar 

  11. K.N. Prasad and A. Sakamoto, Experientia34, 1575 (1978).

    Article  CAS  PubMed  Google Scholar 

  12. K.N. Prasad, R. Prasad, N. Prasad, J.E. Harrell, Radiology, submitted for publication.

  13. A. Sakamoto, K.N. Prasad, Cancer Res.32, 532 (1962).

    Google Scholar 

  14. B. Mendel, M. Bauch and F. Strelitz, Klin. Wschr.10, 116 (1931).

    Google Scholar 

  15. M.A. Apple and D.M. Greenberg, Cancer Chemotherapy Rept.52, 687 (1968).

    CAS  Google Scholar 

  16. B.C. Giovanella, W.A. Lohman and C. Heidelberger, Cancer Res.30, 1623 (1970).

    CAS  PubMed  Google Scholar 

  17. A.C. Sartorelli, E.J. Schoolar, Jr, and P.F. Kruse, Jr, Proc. Soc. exp. Biol. Med.104, 266 (1960).

    Article  CAS  PubMed  Google Scholar 

  18. A.C. Aisenberg and H.P. Morris, Nature191, 1314 (1961).

    Article  CAS  PubMed  Google Scholar 

  19. H. Eagle, S. Barban and M. Levy, J. biol. Chem.233, 551 (1958).

    Article  CAS  PubMed  Google Scholar 

  20. E.G. Goldberg and S.P. Colowick, J. biol. Chem.240, 2786 (1965).

    Article  CAS  PubMed  Google Scholar 

  21. G. Weber and J.A. Lea, in: Methods in Cancer Research, pp. 523. Ed. H. Busch. New York, Academic Press, 1967.

    Google Scholar 

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Authors and Affiliations

  1. Department of Radiology, University of Colorado Medical Center, 4200 East 9th Avenue, 80262, Denver, Colorado, USA

    K. N. Prasad

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  1. K. N. Prasad
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Prasad, K.N. Effect of sodium butyrate in combination with X0irradiation, chemotherapeutic and cyclic AMP stimulating agents on neuroblastoma cells in culture. Experientia 35, 906–908 (1979). https://doi.org/10.1007/BF01955141

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