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The effect of chloroquine upon the developing lens

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Summary

Applied to the developing lens of the 14-day-old chick embryo, in organ culture conditions, chloquine prevented the elongation of the primary lens fibres, destroyed the equatorial ones and provoked vacuolisation and/or destruction in the epithelial cells.

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Authors and Affiliations

  1. The Department of Histology and Cell Biology Sackler School of Medicine, Tel-Aviv University, 61999, Ramat Aviv, Israel

    L. Barr-Nea, Y. R. Barishak & S. Riklis

  2. Mitrani Foundation Eye Pathology Laboratory Sackler School of Medicine, Tel-Aviv University, 61999, Ramat Aviv, Israel

    L. Barr-Nea, Y. R. Barishak & S. Riklis

  3. Chaim Sheba Medical Center, Sackler School of Medicine, Tel-Aviv University, 61999, Ramat Aviv, Israel

    L. Barr-Nea, Y. R. Barishak & S. Riklis

Authors
  1. L. Barr-Nea
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  2. Y. R. Barishak
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  3. S. Riklis
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Additional information

This work was supported by a grant from the office of the Chief Scientist, Ministry of Health, Israel

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Barr-Nea, L., Barishak, Y.R. & Riklis, S. The effect of chloroquine upon the developing lens. Experientia 35, 903–904 (1979). https://doi.org/10.1007/BF01955139

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  • DOI: https://doi.org/10.1007/BF01955139

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