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Hyperosmolar coma as etiological factor in the CNS radiation syndrome of rats

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Summary

Supralethal dose of whole-body or trunk but not head-irradiation in rats induced hyperosmolar coma accompanied by hypernatremia and hyperkalemia. This clinical entity has presented the symptoms of the CNS radiation syndrome with a characteristic short survival time.

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Literatur

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Authors and Affiliations

  1. Departments of Physiology and Biophysics, and Radiology, Georgetown University, School of Medicine and Dentistry, 20007, Washington, D. C., USA

    J. Kabal, L. P. Kirschner, L. J. Parkhurst & D. E. Wyant

  2. George's General Hospital and Medical Center, 20785, Cheverly, Maryland, USA

    J. Kabal

Authors
  1. J. Kabal
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  2. L. P. Kirschner
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  3. L. J. Parkhurst
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  4. D. E. Wyant
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Kabal, J., Kirschner, L.P., Parkhurst, L.J. et al. Hyperosmolar coma as etiological factor in the CNS radiation syndrome of rats. Experientia 35, 901–902 (1979). https://doi.org/10.1007/BF01955138

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  • DOI: https://doi.org/10.1007/BF01955138

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