Summary
Cortisone acetate (25 μg/g b.wt/day) administration to 8-day-old suckling mice induces a premature increase of trehalase activity along the entire small intestine. On the other hand, thyroxine (1 μg/g b.wt/day) is unable to provoke a precocious increase of trehalase activity. Trehalase appears to be the only brush border membrane disaccharidase controlled solely by glucocorticoid hormones during the postnatal maturation of the intestine.
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Supported by grant MA-5969 from the Medical Research Council of Canada to D.M. C.M. is a recipient of a studentship from MRC of Canada.
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Malo, C., Ménard, D. Effects of cortisone and thyroxine on intestinal trehalase activity in infant mouse. Experientia 35, 874–875 (1979). https://doi.org/10.1007/BF01955121
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DOI: https://doi.org/10.1007/BF01955121