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Lack of effect of neurotransmitters on cyclic AMP phosphodiesterase activity in an insect CNS

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Summary

The inhibition of cyclic nucleotide phosphodiesterase from the nerve cord ofManduca sexta was studied using theophylline as a model compound. 11 putative neurotransmitters had no effect on enzyme activity.

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Literatur

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Author information

Author notes

  1. D. P. Taylor

    Present address: Biologic Research, Mead Johnson & Company, 47721, Evansville, Indiana

  2. Denise E. Roberts

    Present address: Department of Biological Chemistry, Harvard University, Cambridge, Massachusetts

Authors and Affiliations

  1. Department of Biochemistry and Biophysics, Oregon State University, 97331, Corvallis, Oregon, USA

    D. P. Taylor & Denise E. Roberts

Authors
  1. D. P. Taylor
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  2. Denise E. Roberts
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Additional information

Supported in part by NIH grant NS-09161-20 to R. W. Newburgh

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Taylor, D.P., Roberts, D.E. Lack of effect of neurotransmitters on cyclic AMP phosphodiesterase activity in an insect CNS. Experientia 35, 856–857 (1979). https://doi.org/10.1007/BF01955109

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  • DOI: https://doi.org/10.1007/BF01955109

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