, Volume 38, Issue 11, pp 1348–1349 | Cite as

Conformation and local anesthetic activity of carbanilates

  • L. Beneš
  • S. Štolc
  • V. Bauer
  • M. Tichý
Short Communications Pharmacology, Toxicology


The influence of spatial configuration on intensity, onset, and duration of anesthetic effect has been observed in some carbanilate local anesthetics of fixed conformation. Synthesis of the carbanilates is described.


Local Anesthetic Local Anesthetic Activity Spatial Configuration Anesthetic Effect Anesthetic Activity 
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Copyright information

© Birkhäuser Verlag 1982

Authors and Affiliations

  • L. Beneš
    • 1
    • 2
  • S. Štolc
    • 1
    • 2
  • V. Bauer
    • 1
    • 2
  • M. Tichý
    • 1
    • 2
  1. 1.Center of Physiological Sciences, Institute of Experimental PharmacologySlovak Academy of SciencesBratislava(Czechoslovakia)
  2. 2.Institute of Organic Chemistry and BiochemistryCzechoslovak Academy of SciencesPrague(Czechoslovakia)

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