Summary
The levels of available norethindrone were found to be similar in women and rabbits after s.c. administration of crystalline and amorphous, norethindrone acetate respectively, and this study indicates that the rabbit may be used as an animal model for further investigation with this contraceptive steroid.
Literatur
N.N. Sarkar, V. Laumas and K.R. Laumas, Endocr. Jap.27, 653 (1980).
S.G. Hillier, P. Jha, K. Griffiths and K.R. Laumas, Contraception15, 473 (1977).
V. Goyal, U.M. Joshi, V.K. Naik and P.K. Devi, Contraception17, 375 (1978).
S. Bhatnagar, U.K. Srivastave, D. Takkar, V.L. Chandra, V. Hingorani and K.R. Laumas, Contraception11, 505 (1975).
V. Laumas, A.K. Jain, P. Jha, S.A. Rahman, D. Kumar, B.K. Malik, N.N. Sarkar, D. Takkar, V. Hingorani and K.R. Laumas, Contraception23, 211 (1981).
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Sarkar, N.N., Laumas, K.R. & Hingorani, V. Bioavailability of norethindrone in women and rabbits after administration of norethindrone acetate through the subcutaneous route. Experientia 38, 1345–1346 (1982). https://doi.org/10.1007/BF01954942
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DOI: https://doi.org/10.1007/BF01954942