Skip to main content
SpringerLink
Log in

Urinary levels of chloroquine in relation to dietary protein

  • Short Communications
  • Biochemistry
  • Published:
Experientia Aims and scope Submit manuscript

Summary

When rats suffering from protein-calorie malnutrition (kwashiorkor) were given chloroquine, urinary levels of unchanged drug increased while chloroquine metabolites decreased. This qpparent inhibition of chloroquine metabolism was eliminated by refeeding the animals.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. Bassir, O., in: Handbook of practical biochemistry, 2nd edn, p. 25, Ibadan University Press, Ibadan 1963.

    Google Scholar 

  2. Morley, D., Bicknell, J., and Woodland, M., Trans. R. Soc. trop. Med. Hyg.62 (1968) 164.

    Article  CAS  PubMed  Google Scholar 

  3. Wood-Walker, R.B., Lancet1 (1970) 299.

    Article  Google Scholar 

  4. Rubin, M., Zvaifler, N., Bernstein, H., and Mansour, A., in: Proc. 2nd int. Congr. of Pharmac., p. 467. Pergamon Press, Oxford 1965.

    Google Scholar 

  5. Adelusi, S.A., and Salako, L.A., J. Pharm. Pharmac.32 (1980) 711.

    Article  CAS  Google Scholar 

  6. Boyd, E.M., Clin. Toxic.2 (1969) 423.

    Article  Google Scholar 

  7. Smith, J.W., Hill, C.H., and Hamilton, P.B., Poultry Sci.50 (1971) 768.

    Article  CAS  Google Scholar 

  8. Sick, D.B., and Carlton, W.W., Am. J. vet. Res.33 (1972) 107.

    Google Scholar 

  9. McChesney, E.W., Conway, W.D., Banks, Jr, W.F., Rogers, J.E., and Shekosky, J.M., J. Pharm. exp. Ther.151 (1966) 482.

    CAS  Google Scholar 

  10. Fletcher, K.A., Baty, J.D., Price Evans, D.A., and Gilles, H.M., Trans. R. Soc. Trop. Med. Hyg.69 (1975) 6.

    CAS  PubMed  Google Scholar 

  11. Kato, R., Oshima, T., and Tomizawa, S., Jap. J. Pharmac.18 (1968) 356.

    Article  CAS  Google Scholar 

  12. Buchanan, N., and Van der Walt, L.A., Am. J. trop. Med. Hyg.26 (1977) 1025.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Nigeria

    S. A. Adelusi

Authors
  1. S. A. Adelusi
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Adelusi, S.A. Urinary levels of chloroquine in relation to dietary protein. Experientia 38, 1326–1327 (1982). https://doi.org/10.1007/BF01954930

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01954930

Keywords

Search

Navigation