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Urushiol components as mediators in DNA strand scission

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Summary

Poison oak urushiol, a mixture of 3-alk(en)ylcatechol derivatives was found to mediate DNA strand scission in the presence of oxygen and with copper(II) chloride as a catalyst. The reactionis believed to occur via activated reduced oxygen produced during oxidation of the catechol into itso-quinone derivative.

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Wasser, C., Silva, F. & Rodriguez, E. Urushiol components as mediators in DNA strand scission. Experientia 46, 500–502 (1990). https://doi.org/10.1007/BF01954246

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  • DOI: https://doi.org/10.1007/BF01954246

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