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D-Aspartate oxidase activity and D-aspartate content in a mutant mouse strain lacking D-amino acid oxidase

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Summary

A mutant mouse strain ddY/DAO− lacks D-amino acid oxidase activity and accumulates free neutral D-amino acids in its tissues. In this study, D-aspartate oxidase activity and D-aspartate content in the tissues of these mutant mice were compared with those of normal mice. No significant difference was observed, indicating that the metabolism of acidic D-amino acids was unaffected in the mutant.

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Author notes

  1. R. Yamada

    Present address: Department of Bioengineering, Nagaoka University of Technology, 940-21, Nagaoka, Niigata, Japan

Authors and Affiliations

  1. Department of Biochemistry, Kyoto Prefectural University of Medicine, 602, Kyoto, Japan

    H. Nagasaki, R. Yamada & A. Iwashima

  2. Department of Microbiology, Dokkyo University School of Medicine, 321-02, Mibu, Tochigi, Japan

    R. Konno & Y. Yasumura

Authors
  1. H. Nagasaki
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  2. R. Yamada
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  3. R. Konno
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  4. Y. Yasumura
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  5. A. Iwashima
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Nagasaki, H., Yamada, R., Konno, R. et al. D-Aspartate oxidase activity and D-aspartate content in a mutant mouse strain lacking D-amino acid oxidase. Experientia 46, 468–470 (1990). https://doi.org/10.1007/BF01954233

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  • DOI: https://doi.org/10.1007/BF01954233

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