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European Journal of Pediatrics

, Volume 152, Issue 9, pp 712–714 | Cite as

Intravenous nicardipine in hypertensive children

  • J. M. Treluyer
  • P. Hubert
  • P. Jouvet
  • S. Couderc
  • M. Cloup
Cardiology Original Papers

Abstract

Fourteen hypertensive patients hospitalized in a paediatric intensive care unit were studied to evaluate safety and hypotensive efficacy of intravenous nicardipine. Systolic and diastolic blood pressure significantly decreased 1 h after the beginning of the treatment (1 μg/kg per minute). Mean decrease in systolic blood pressure during the first 24 h was between 9.9% and 13.4% of the initial value. Mean lowering of diastolic blood pressure was between 16.7% and 25.6%. Nicardipine did not significantly affect heart rate with dose of 1 μg/kg per minute. No clinical side-effects were observed. Nicardipine could be a first line drug for the treatment of hypertension in paediatric intensive care units.

Key words

Nicardipine Children Hypertension 

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Copyright information

© Springer-Verlag 1993

Authors and Affiliations

  • J. M. Treluyer
    • 1
  • P. Hubert
    • 1
  • P. Jouvet
    • 1
  • S. Couderc
    • 1
  • M. Cloup
    • 1
  1. 1.Réammation PédiatriqueHôpital Necker-Enfants MaladesParis, Cédex 15France

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