, Volume 36, Issue 2, pp 243–244 | Cite as

Trimethoprim enhances the antibacterial activity of nalidixic and oxolinic acids and delays the emergence of resistance

  • A. Bertolini
  • M. Castelli
  • Susanna Genedani
  • M. Garuti


Trimethoprim enhances the in vitro activity of nalidixic and oxolinic acids against some representative pathogenic microorganisms, including those which are most frequently responsible for urinary tract infections, and delays the emergence of resistance in many of them.


Urinary Tract Tract Infection Antibacterial Activity Urinary Tract Infection Trimethoprim 
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Copyright information

© Birkhäuser Verlag 1980

Authors and Affiliations

  • A. Bertolini
    • 1
  • M. Castelli
    • 1
  • Susanna Genedani
    • 1
  • M. Garuti
    • 1
  1. 1.Institute of PharmacologyUniversity of ModenaModena(Italy)

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