Summary
The i.v. injection of bacterial endotoxin into dogs was found to cause a rapid increase in plasma levels of infused α-aminoisobutyric acid. The findings suggest that nonmetabolic factors (tissue uptake, fluid shifts) influence amino acid distribution during endotoxemia.
Similar content being viewed by others
References
W.R. Beisel, Am. J. clin. Nutr.30, 1236 (1977).
R.W. Wannemacher, Am. J. clin. Nutr.30, 1269 (1977).
A.C. Groves, L.I. Wolf, P.J. O'Regan, C. Beach, C. Hasinoff and W.H. Sutherland, Surgery76, 533 (1974).
R.E. Kuttner and J.J. Spitzer, J. surg. Res.25, 166 (1978).
M.W. Noall, T.R. Riggs, L.M. Walker and H.N. Christensen, Science126, 1002 (1957).
D.L. Oxender and H.N. Christensen, J. biol. Chem.238, 3686 (1963).
R. Kuttner, J. Sims and M.W. Gordon, J. Neurochem.6, 311 (1961).
Author information
Authors and Affiliations
Additional information
This investigation was supported in part by the Office of Naval Research, Contract N0001476CO132. R.E.K., Postdoctoral Fellow, supported by HL07090. Address correspondence to J.J.S.
Rights and permissions
About this article
Cite this article
Kuttner, R.E., Spitzer, J.J. The effect of endotoxin on plasma α-aminoisobutyric acid. Experientia 36, 215–216 (1980). https://doi.org/10.1007/BF01953739
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01953739