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Experientia

, Volume 38, Issue 8, pp 968–970 | Cite as

Orally administered melatonin stimulates the 3α/β-hydroxysteroid oxidoreductase but not the 5α-reductase in the ventral prostate and seminal vesicles of pinealectomized rats

  • H. -J. Horst
  • A. Buck
  • K. -U. Adam
Specialia Endocrinologica

Summary

Pinealectomized rats were treated orally with melatonin (MEL) for 14 days. Prostates and seminal vesicles were investigated for the activity of the δ 4-3-ketosteroid-5α-oxidoreductase (5α-R) and of the 3α/β-hydroxysteroid-oxidoreductase (3α-HSO). The activity of the 3a-HSO was significantly stimulated (p<0.01, Friedman test) when compared to controls. The activity of the 5α-R did not change significantly.

Keywords

Melatonin Seminal Vesicle Oxidoreductase Friedman Test Ventral Prostate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Birkhäuser Verlag 1982

Authors and Affiliations

  • H. -J. Horst
    • 1
  • A. Buck
    • 1
  • K. -U. Adam
    • 1
  1. 1.Abteilung Klinische Chemie2. Medizinische UniversitätsklinikHamburg 20Germany

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