Elimination and metabolism of dimethylnitrosamine (DMN) byXenopus laevis and other amphibians
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The elimination of (14C)-DMN after i.p. injection intoXenopus was measured, as was the metabolism in vitro of (14C)-DMN by liver fromXenopus and 9 other amphibian species. In view of its rapid elimination from the body and low rate of metabolism byXenopus liver in vitro, DMN is unlikely to be toxic or carcinogenic inXenopus.
KeywordsAmphibian Species Rapid Elimination Dimethylnitrosamine
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