Experientia

, Volume 35, Issue 12, pp 1645–1647 | Cite as

Time courses and refractoriness of enhanced vascular permeability induced by histamine, serotonin and bradykinin in synovialis of the rat

  • L. P. Bignold
  • A. W. J. Lykke
Article
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Summary

Enhanced vascular permeability induced in synovialis of the rat by histamine and serotonin lasts 5–15 min and that induced by bradykinin less than 5 min. Synovialis of the rat becomes refractory to the permeability effects of repeated doses of each of these substances in the hour following initial application.

Keywords

Permeability Serotonin Histamine Bradykinin Vascular Permeability 

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Copyright information

© Birkhäuser Verlag 1979

Authors and Affiliations

  • L. P. Bignold
    • 1
  • A. W. J. Lykke
    • 1
  1. 1.School of PathologyUniversity of New South WalesKensingtonAustralia

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