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Silymarin, an inhibitor of prostaglandin synthetase

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Silybin (I), silydianin (II) and silychristin (III), the main constituents of silymarin, inhibit the formation of prostaglandins in vitro. The inhibition is log-linearly dependent on the concentration of the effectors.

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F. Fiebrich, Thesis, University of Vienna 1977.

H. Koch, Dt. ApothZtg118, 1844 (1978); reported in part at the Colloquium Pharmaceuticum in Münster, 21st November 1978.

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Fiebrich, F., Koch, H. Silymarin, an inhibitor of prostaglandin synthetase. Experientia 35, 1550–1552 (1979).

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