Experientia

, Volume 32, Issue 10, pp 1347–1348 | Cite as

Release of immuno-reactive and biologically active LH from fetal mouse pituitary in response to synthetic gonadotropin releasing factor (LRF)

  • G. Pointis
  • J. A. Mahoudeau
Endocrinologica

Summary

In an incubation system, LRF stimulated significantly the release of LH from 18-day-old mouse fetal pituitary. This LRF-induced LH release, measured by RIA in the incubation medium was able to increase the testosterone production by age-matched fetal testes. This data suggests that the hypothalamo-hypophyseal-testicular axis is functional at the end of mouse prenatal life.

Keywords

Testosterone Incubation Medium Testosterone Production Fetal Mouse Incubation System 

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Copyright information

© Birkhäuser Verlag 1976

Authors and Affiliations

  • G. Pointis
    • 1
    • 2
  • J. A. Mahoudeau
    • 1
    • 2
  1. 1.Laboratoire de Chimie HormonaleMaternité de Port-RoyalParis(France)
  2. 2.Centre de Recherches EndocrinologiquesHôpital CochinParis(France)

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