, Volume 32, Issue 10, pp 1347–1348 | Cite as

Release of immuno-reactive and biologically active LH from fetal mouse pituitary in response to synthetic gonadotropin releasing factor (LRF)

  • G. Pointis
  • J. A. Mahoudeau


In an incubation system, LRF stimulated significantly the release of LH from 18-day-old mouse fetal pituitary. This LRF-induced LH release, measured by RIA in the incubation medium was able to increase the testosterone production by age-matched fetal testes. This data suggests that the hypothalamo-hypophyseal-testicular axis is functional at the end of mouse prenatal life.


Testosterone Incubation Medium Testosterone Production Fetal Mouse Incubation System 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Birkhäuser Verlag 1976

Authors and Affiliations

  • G. Pointis
    • 1
    • 2
  • J. A. Mahoudeau
    • 1
    • 2
  1. 1.Laboratoire de Chimie HormonaleMaternité de Port-RoyalParis(France)
  2. 2.Centre de Recherches EndocrinologiquesHôpital CochinParis(France)

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