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Experientia

, Volume 32, Issue 10, pp 1295–1297 | Cite as

Transmural pressure as a determinant of basic intrinsic heart rate

  • C. L. Pathak
Physiologica
  • 11 Downloads

Summary

It was observed the heart rate was minimum at zero transmural pressure. The mean heart rate at zero transmural pressure was 23±5/min. This mean heart rate increased from 23±5/min to a peak value of 40±6/min (74% acceleratin) when the transmural pressure was raised from 0 to +4 mm Hg and to a similar peak value of 36±8/min (56% acceleration) when the transmural pressure was lowered from 0 to −4 mm Hg. The peak values attained at ±4 mm Hg were higly significant (p<0.001). It is concluded that the heart rate at zero transmural pressure represents the basic intrinsic pacemaker frequency independent of neural, humoral, thermal and haemodynamically induced mechanical influences.

Keywords

Heart Rate Transmural Pressure Similar Peak Mechanical Influence Intrinsic Heart Rate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Birkhäuser Verlag 1976

Authors and Affiliations

  • C. L. Pathak
    • 1
  1. 1.Department of Physiology, Biophysics and BiochemistryS. N. Medical CollegeJodhpurIndia

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