Summary
A regulatory element tightly linked to theGpdh locus inDrosophila melanogaster has been isolated from a natural population. Flies homozygous for second chromosomes bearing the element,H31, have half the GPDH activity of normal homozygotes. Heterozygotes betweenH31 andF orS alleles exhibit dominance in GPDH activity. Heterozygotes betweenH31, F orS andDf(2L) GdhA have half the diploid level. The contribution of theS allele to the activity inS/H31 heterozygotes is more than four times that ofH31. The regulatory element distinguishingH31 is tightly linked to theGpdh + locus.
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Gibson, J.B., Wilks, A.V., Cao, A. et al. Dominance for enzyme activity inDrosophila melanogaster. Experientia 42, 191–192 (1986). https://doi.org/10.1007/BF01952463
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DOI: https://doi.org/10.1007/BF01952463