, Volume 42, Issue 2, pp 162–163 | Cite as

Acute cold exposure increases the glucagon sensitivity of thermogenic metabolism in the rat

  • R. J. Howland
Short Communications Biochemistry and Biophysics, Metabolism, Neurobiology, Pharmacology


Administration of glucagon to rats at 25°C had no effect upon their VO2 while administration of noradrenaline or noradrenaline plus glucagon raised the VO2-At 5°C, noradrenaline had no effect upon the cold-enhanced VO2, while glucagon caused a rise of 13.7% implying increased glucagon sensitivity at 5°C. The glucagon-induced enhancement of VO2 was abolished by concurrent administration of noradrenaline.

Key words

Glucagon theromogenesis cold-exposure VO2 


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Copyright information

© Birkhäuser Verlag Basel 1986

Authors and Affiliations

  • R. J. Howland
    • 1
  1. 1.Division of Nutrition and Food Science, Department of BiochemistryUniversity of SureyGuildfordEngland

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