Summary
The release of insulin which occurred in response to arginine, in the conscious calf, differed from that which occurs in response to glucose in that it was not significantly affected by either adrenergic or muscarinic blocking agents. Release of pancreatic glucagon was reduced by pretreatment with phentolamine.
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Bloom, S. R., and Edwards, A. V., J. Physiol.314 (1981) 37.
Bloom, S. R., and Edwards, A. V., J. Physiol.362 (1985) 311.
Porte, D. Jr, J. clin. Invest.46 (1967) 86.
Porte, D. Jr, Diabetes16 (1967) 150.
Unger, R. H., and Lefebure, P. J., in: Glucagon Molecular Physiology, Clinical and Therapeutic Implications, p. 213. Eds P. J. Lefebure and R. H. Unger. Pergamon Press, New York 1972.
Bloom, S. R., and Edwards, A. V., J. Physiol.346 (1984) 533.
Snedecor, G. W., and Cochran, W. G., Statistical methods, 6th Edn. Ames. Iowa State College Press 1967.
Schwartz, T. W., Holst, J. J., Fahrenkrug, J., Jensen, S. L., Nielsen, S. E. N., Rehfeld, J. F., de Muckadell, O. B. F., and Stadill, F., J. clin. Invest.61 (1982) 781.
Edwards, A. V. in: Recent Advances in Physiology, vol. 10, p. 277. Ed. P. F. Baker. Churchill Livingstone, London.
Edwards, A. V., and & Bloom, S. R., Trends autonom. Pharmac., in press.
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This work was supported by the British Diabetic Association. It is a particular pleasure to acknowledge the skilled assistance provided by Messrs P. M. M. Bircham and G. P. McGregor.
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Edwards, A.V., Bloom, S.R. The role of the autonomic nervous system in mediating pancreatic endocrine responses to arginine in the calf. Experientia 42, 158–160 (1986). https://doi.org/10.1007/BF01952445
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DOI: https://doi.org/10.1007/BF01952445