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Influences of the chemical structure on the activity of new inhibitory compounds of the angiotensin-converting enzyme

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  • Biochemistry and Biophysics, Metabolism, Neurobiology, Pharmacology
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Summary

The ACE inhibitory activity of some perimidines, chinazolinones and amidinohydrazones is described. Relations were found between the chemical structure and the inhibitory activity on the ACE.

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Authors and Affiliations

  1. Institute of Drug Research, Academy of Sciences of the GDR, DDR-1136, Berlin, Germany

    W. -E. Siems, G. Heder, K. D. Jentzsch & P. Oehme

  2. Institute of Biochemistry of Plants, Academy of Sciences of the GDR, DDR-4010, Halle (Saale), Germany

    U. Burkhardt & S. Johne

  3. Section of Pharmacy, Ernst-Moritz-Arndt-University Greifswald, DDR-2200, Greifswald, Germany

    H. Kühmstedt, K. Kottke & I. Wunderlich

Authors
  1. W. -E. Siems
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  2. G. Heder
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  3. K. D. Jentzsch
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  4. U. Burkhardt
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  5. S. Johne
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  6. H. Kühmstedt
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  7. K. Kottke
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  8. I. Wunderlich
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  9. P. Oehme
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Siems, W.E., Heder, G., Jentzsch, K.D. et al. Influences of the chemical structure on the activity of new inhibitory compounds of the angiotensin-converting enzyme. Experientia 42, 141–144 (1986). https://doi.org/10.1007/BF01952436

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  • DOI: https://doi.org/10.1007/BF01952436

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