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Experientia

, Volume 42, Issue 2, pp 138–139 | Cite as

Proton and potassium fluxes in rat red blood cells incubated with sugar phosphates

  • L. Galzigna
  • M. P. Rigobello
Short Communications Biochemistry and Biophysics, Metabolism, Neurobiology, Pharmacology

Summary

Fructose-1,6-diphosphate counteracts potassium ejection and proton uptake induced in rat red blood cells by valinomycin and an uncoupler. The effect on potassium ejection is reduced in the presence of ouabain and divalent cations.

Key words

Rat erythrocytes K+-flux H+-flux fructose-1,6-diphosphate potassium ejection 

Literature

  1. 1.
    Rigobello, M. P., Deana, R., and Galzigna, L., in: Advances in Pathology, p. 215. Ed. E. Levy. Pergamon Press, Oxford 1982.Google Scholar
  2. 2.
    Galzigna, L., Rigobello, M. P., Scutari, G., and Burlina, A., in press 1985.Google Scholar
  3. 3.
    Lazzarino, G., Cattani, L., Costrini, R., Mulieri, L., Candiani, A., and Galzigna, L., Clin. Biochem.17 (1984) 42.CrossRefPubMedGoogle Scholar
  4. 4.
    Cattani, L., Costrini, R., Cerilli, C., Rigobello, M. P., Bianchi, M., and Galzigna, L., Agressologie21 (1980) 263.PubMedGoogle Scholar
  5. 5.
    Lockwood, R. V., and Lum, B. K. B., J. Pharm. exp. Ther.189 (1974) 119.Google Scholar
  6. 6.
    Hers, H. G., and Hue, L., A. Rev. Biochem.52 (1983) 617.CrossRefGoogle Scholar
  7. 7.
    Beutler, E., in: Red Cell Metabolism, p. 11. Grune & Stratton, New York 1971.Google Scholar
  8. 8.
    Harris, E. J., and Pressman, B. C., Nature216 (1967) 918.PubMedGoogle Scholar
  9. 9.
    Isern, M., and Romero, P. J., J. Physiol.265 (1977) 411.Google Scholar
  10. 10.
    Roufogalis, B. D., Can. J. Physiol. Pharmac.57 (1979) 1331.Google Scholar
  11. 11.
    Roth, Z., Chayen, N., and Dikstein, S., Int. Rev. Cytol.85 (1983) 39.PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag Basel 1986

Authors and Affiliations

  • L. Galzigna
    • 1
  • M. P. Rigobello
    • 1
  1. 1.Institute of Biological ChemistryUniversity of PadovaPadovaItaly

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