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Calcium accelerates cholesterol phase transitions in analog bile

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Summary

Analog bile supersaturated with cholesterol was constituted, filtered and divided into equal portions containing no calcium or calcium, 2.5–15 mM. Aliquots were removed over the next 48 h and filtrates analyzed for cholesterol, bile acid and lecithin. Calcium accelerated cholesterol loss from solution in a dose-related fashion.

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Authors and Affiliations

  1. University of Utah School of Medicine and College of Pharmacy, 84132, Salt Lake City, Utah, USA

    M. M. Berenson & J. R. Cardinal

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  1. M. M. Berenson
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  2. J. R. Cardinal
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Berenson, M.M., Cardinal, J.R. Calcium accelerates cholesterol phase transitions in analog bile. Experientia 41, 1328–1330 (1985). https://doi.org/10.1007/BF01952079

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  • DOI: https://doi.org/10.1007/BF01952079

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