Summary
In adult sheep, the frequency of the migrating motor complexes (MMC) was increased by the duodenal administration of methysergide, but not affected by other 5-HT1 or 5-HT2 antagonists. This reset of the MMC pattern at a faster rhythm suggests a selective action on the enteric neuronal serotoninergic mechanism modulating the pacing of the gut cyclic motor activity.
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Ruckebusch, Y., Bardon, T. The cyclic motor activity of the ovine gut: its reset at a faster rhythm. Experientia 40, 819–820 (1984). https://doi.org/10.1007/BF01951969
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DOI: https://doi.org/10.1007/BF01951969